I. Information of ICE
ICEberg ID669
Name ICE_515_tRNALys This ICE is derived from experimental literature
OrganismStreptococcus agalactiae 515
Size (bp)-
GC content [Genome] (%)-
Insertion sitetRNALys
Species that ICE can be transferred toStreptococcus agalactiae Nem316; Streptococcus agalactiae COH1Streptococcus pyogenes (ATCC 12202)
Nucleotide SequenceAAJP01000002; AAJP01000028 (partial ICE sequence)
Putative oriT region -
Putative relaxase -

II. ICE interaction with IME/CIME/

The Interaction Network among ICE/IME/CIME

Detailed Informatioin of the Interaction Network
# ICE  Inter_Ele [Type] Methods Donors Recipients Exper_Ref 
1ICE_515_tRNALys CIME_Nem316_tRNALys [CIME] experimentalin cis Streptococcus agalactiae Streptococcus agalactiae; Streptococcus pyogenes 23275243

experimental This is an interactioin derived from experimental literature

The graph information of ICE_515_tRNALys components from AAJP01000002
Incomplete gene list of ICE_515_tRNALys from AAJP01000002
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
1SAL_202232384..33100 [+], 717transcriptional regulator, MerR family
2SAL_202333139..33609 [-], 471acetyltransferase, GNAT family
3SAL_202433581..34039 [-], 459MutT/nudix family protein
4SAL_202534026..34169 [-], 144conserved hypothetical protein
5SAL_202634175..34645 [-], 471conserved hypothetical protein
6SAL_202734972..35463 [+], 492acetyltransferase, GNAT family
7SAL_202835456..36724 [+], 1269ATPase, AAA family
8SAL_202937179..38300 [-], 1122site-specific recombinase, phage integrase familyIntegrase 
9SAL_203038350..38676 [-], 327Domain of unknown function (DUF771) superfamily
10SAL_203138869..39501 [-], 633conserved hypothetical protein
11SAL_203239577..40119 [-], 543Unknown
12SAL_203340342..40503 [-], 162putative cell wall surface anchor family protein
13SAL_203440605..41921 [-], 1317conserved hypothetical protein
14SAL_203541923..42792 [-], 870putative DNA adenine methylase
15SAL_203642888..43667 [-], 780cell wall surface anchor signal proteinPrgC, T4SS component 
16SAL_203743684..44232 [-], 549conserved hypothetical protein
17SAL_203844232..45605 [-], 1374CHAP domain familyPrgK, T4SS component 
18SAL_203946101..48101 [-], 2001putative membrane proteinYddG, T4SS component 
19SAL_204048117..50618 [-], 2502conjugal transfer protein, interruption-CYddE, T4SS component 
20SAL_204150639..51013 [-], 375conserved hypothetical proteinYddD, T4SS component 
21SAL_204251053..51319 [-], 267conserved hypothetical protein
22SAL_204351340..52293 [-], 954conserved hypothetical proteinYddB, T4SS component 
23SAL_204452346..52600 [-], 255conserved hypothetical protein
24SAL_204552593..52859 [-], 267Uncharacterized ACR, COG2161 subfamily
25SAL_204653004..53477 [-], 474conserved hypothetical protein
26SAL_204753481..53966 [-], 486conserved hypothetical protein
27SAL_204854019..54291 [-], 273conserved hypothetical protein
28SAL_204954423..54776 [-], 354transcriptional regulator, Cro/CI family
29SAL_205054769..54999 [-], 231transcriptional regulator, Cro/CI family
30SAL_205154986..55363 [-], 378conserved hypothetical protein
31SAL_205255379..56611 [-], 1233transcriptional regulator, Cro/CI familyRelaxase, MOBT Family
32SAL_205356899..58560 [-], 1662FtsK/SpoIIIE family proteinYdcQ, T4SS component 
33SAL_205458637..59098 [-], 462conserved hypothetical protein
34SAL_205559120..59416 [-], 297conserved hypothetical protein
35SAL_205659476..62067 [-], 2592cell wall surface anchor family proteinPrgB, T4SS component 
36SAL_205762156..64417 [-], 2262UnknownPrgA, T4SS component 
37SAL_205864433..64696 [-], 264conserved hypothetical protein
38SAL_205964716..65177 [-], 462Unknown
39SAL_206065162..65473 [-], 312conserved hypothetical protein
40SAL_206165466..65897 [-], 432transcriptional regulator, Cro/CI family

The graph information of ICE_515_tRNALys components from AAJP01000028
Incomplete gene list of ICE_515_tRNALys from AAJP01000028
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
1SAL_206665..283 [-], 219transcriptional regulator, Cro/CI family
2SAL_20671414..1728 [+], 315transcriptional regulator, Cro/CI family
3SAL_20681741..1893 [-], 153conserved hypothetical protein
4SAL_20691928..2266 [+], 339transcriptional regulator, Cro/CI family
5SAL_20702273..2695 [+], 423Unknown
6SAL_20712770..3138 [-], 369putative lipoprotein
7SAL_20723142..3480 [-], 339Unknown
8SAL_20733477..3770 [-], 294putative DNA-damage-inducible protein J
9SAL_20744304..5062 [-], 759CAMP factor
10SAL_20755359..6666 [-], 1308transposase, ISL3 family
11carB6826..8466 [-], 1641carbamoyl-phosphate synthase, large subunit
12SAL_20778495..8887 [-], 393mercuric resistance operon regulatory protein MerR
13SAL_20789593..11161 [+], 1569Mn2+/Fe2+ transporter, NRAMP family
14SAL_207911729..12451 [-], 723putative membrane protein
15SAL_208012455..13072 [-], 618ABC transporter, ATP-binding protein
16SAL_208113130..13240 [-], 111conserved hypothetical protein
17SAL_208213759..14613 [-], 855streptomycin resistance protein
18SAL_208314792..15184 [-], 393conserved hypothetical protein
19SAL_208416034..16369 [-], 336transcriptional regulator, PadR family domain protein
20SAL_208516891..17442 [-], 552acetyltransferase, GNAT family
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences0Fasta
(1) Puymege A; Bertin S; Chuzeville S; Guedon G; Payot S (2013). Conjugative transfer and cis-mobilization of a genomic island by an integrative and conjugative element of Streptococcus agalactiae. J Bacteriol. 195(6):1142-51. [PudMed:23275243]
(2) Chuzeville S; Puymege A; Madec JY; Haenni M; Payot S (2012). Characterization of a New CAMP Factor Carried by an Integrative and Conjugative Element in Streptococcus agalactiae and Spreading in Streptococci. PLoS One. 7(11):e48918. [PudMed:23152820] experimental
(3) Brochet M; Couve E; Glaser P; Guedon G; Payot S (2008). Integrative conjugative elements and related elements are major contributors to the genome diversity of Streptococcus agalactiae. J Bacteriol. 190(20):6913-7. [PudMed:18708498] experimental in_silico
experimental experimental literature
in_silico in silico analysis literature