ICEberg
I. Information of ICE
ICEberg ID401
Name CTn5 This is a predicted ICE derived from literature
FamilyUnclassified
OrganismClostridium difficile 630
Size (bp)43503
GC content [Genome] (%)32.7
Insertion siteCD630_18440
Function-
Species that ICE can be transferred to-
Nucleotide SequenceAM180355 (complete ICE sequence in this genome)
Replicon chromosome (4290252 bp, BioProject:78) [NC_009089]
Genome coordinates2137789..2181291 
Putative oriT region -
Putative relaxase coordinates: 2170086..2171417; Locus tag: CD630_18690;  Family:  MOBP


II. ICE interaction with IME/CIME/

The interaction information of CTn5 is not available.



The graph information of CTn5 components from AM180355
Complete gene list of CTn5 from AM180355
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1CD630_184202134424..2135170 [+], 747conserved hypothetical protein, DUF218 family
2CD630_184302135119..2135427 [-], 309conserved hypothetical protein
3CD630_184402136229..2185930 [+], 49702Fragment of conserved hypothetical protein
4CD630_184412137462..2137770 [+], 309Fragment of putative methyltransferase (N-terminal region)
5CD630_184502137789..2138070 [+], 282putative membrane protein Tn1549-like,CTn5-Orf1
6CD630_184602138111..2138629 [+], 519putative conjugative transposon protein Tn1549-like, CTn5-Orf2
7CD630_184702138730..2139740 [+], 1011putative conjugative transposon protein Tn1549-like, CTn5-Orf3
8CD630_184802139742..2140227 [+], 486putative conjugative transposon protein Tn1549-like, CTn5-Orf4Integrase 
9CD630_184902140266..2142005 [+], 1740putative conjugative transfer protein Tn1549-like, CTn5-Orf5
10CD630_185002142169..2143035 [+], 867Transcriptional regulator, AraC family; Tn1549-like, CTn5-Orf6
11CD630_185102143244..2143555 [+], 312putative single-strand DNA-binding protein Tn1549-like, CTn5-Orf7
12CD630_185202143559..2143774 [+], 216putative conjugative transposon protein Tn1549-like, CTn5-Orf8
13CD630_185302143794..2144657 [+], 864putative membrane protein Tn1549-like,CTn5-Orf9
14CD630_185402144675..2144935 [+], 261putative conjugative transposon protein Tn1549-like, CTn5-Orf10
15CD630_185502144939..2145328 [+], 390putative conjugative transposon protein Tn1549-like, CTn5-Orf11
16CD630_185602145240..2147669 [+], 2430putative hydrolase Tn1549-like, CTn5-Orf12PrgJ, T4SS component 
17CD630_185702147674..2149836 [+], 2163putative cell wall hydrolase Tn1549-like,CTn5-Orf13Orf14_Tn, T4SS component 
18CD630_185712149848..2150081 [+], 234putative conjugative transposon protein Tn1549-like, CTn5-Orf14
19CD630_185802150071..2151642 [+], 1572putative cell surface protein Tn1549-like,CTn5-Orf15
20CD630_185902151738..2153444 [+], 1707DNA topoisomerase protein, type IA,Tn1549-like, CTn5-Orf16
21CD630_185912153528..2153713 [+], 186Transcriptional regulator, AbrB family; Tn1549-like, CTn5-Orf17
22CD630_186002153747..2154793 [+], 1047putative conjugative transposon protein DUF1016 family, Tn1549-like, CTn5-Orf18
23CD630_186102154904..2155710 [+], 807putative conjugative transposon protein Tn1549-like, CTn5-Orf19
24CD630_186202155823..2164804 [+], 8982putative DNA/RNA helicase Tn1549-like,CTn5-Orf21
25CD630_186302164847..2165506 [+], 660putative single-strand DNA-binding protein Tn1549-like, CTn5-Orf22
26CD630_186402165646..2165876 [+], 231Transcriptional regulator, HTH-type Tn1549-like, CTn5-Orf23
27CD630_186502166079..2167701 [+], 1623putative DNA recombination protein Tn1549-like,CTn5-Orf24
28CD630_186602167698..2168765 [+], 1068putative conjugative transposon protein tn1549-like, CTn5-Orf25
29CD630_186702168793..2169254 [+], 462putative conjugative transposon protein Tn1549-like, CTn5-Orf26
30CD630_186802169244..2170050 [+], 807putative conjugative transposon protein Tn1549-like, CTn5-Orf27
31CD630_186902170086..2171417 [-], 1332putative endonuclease relaxase Tn1549-like,CTn5-Orf28Relaxase, MOBP Family
32CD630_187002171423..2171773 [-], 351putative conjugative transposon protein Tn1549-like, CTn5-Orf29
33CD630_187102172097..2173254 [+], 1158putative oxidoreductase Tn1549-like,CTn5-Orf30
34CD630_187112173276..2173428 [+], 153putative conjugative transposon protein Tn1549-like, CTn5-Orf31
35CD630_187202173421..2174311 [+], 891putative iron-sulfur binding protein Tn1549-like, CTn5-Orf32
36vexP12174330..2175607 [+], 1278ABC-type transport system, permease Tn1549-like, CTn5-Orf33
37vexP22175617..2176273 [+], 657ABC-type transport system, ATP-binding protein Tn1549-like, CTn5-Orf34
38vexP32176273..2177649 [+], 1377ABC-type transport system, permease Tn1549-like, CTn5-Orf35
39vncR2177747..2178400 [+], 654Two-component response regulator; Tn1549-like,CTn5-Orf36
40vncS2178397..2179716 [+], 1320Two-component sensor histidine kinase; Tn154c-like, CTn5-Orf37
41CD630_187802180240..2180650 [+], 411putative sigma factor Tn1549-like, CTn5-Orf38
42CD630_187822181139..2181291 [+], 153putative conjugative transposon protein Tn1549-like, CTn5-Orf39
43CD630_184402136229..2185930 [+], 49702Fragment of conserved hypothetical protein
44CD630_187812181392..2183038 [+], 1647Fragment of conserved hypothetical protein (N-terminal region)
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins38Fasta
(1) Sebaihia M; Wren BW; Mullany P; Fairweather NF; Minton N; Stabler R; Thomson NR; Roberts AP; Cerdeno-Tarraga AM; Wang H; Holden MT; Wright A; Churcher C; Quail MA; Baker S; Bason N; Brooks K; Chillingworth T; Cronin A; Davis P; Dowd L; Fraser A; Feltwell T; Hance Z; Holroyd S; Jagels K; Moule S; Mungall K; Price C; Rabbinowitsch E; Sharp S; Simmonds M; Stevens K; Unwin L; Whithead S; Dupuy B; Dougan G; Barrell B; Parkhill J (2006). The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 38(7):779-86. [PudMed:16804543]