ICEberg
I. Information of ICE
ICEberg ID398
Name CTn1 This is a predicted ICE derived from literature
FamilyTn916
OrganismClostridium difficile 630
Size (bp)24482
GC content [Genome] (%)38.47
Insertion site-
Function-
Species that ICE can be transferred to-
Nucleotide SequenceAM180355 (complete ICE sequence in this genome)
Replicon chromosome (4290252 bp, BioProject:78) [NC_009089]
Genome coordinates428851..453332 
Putative oriT region -
Putative relaxase coordinates: 449360..450472; Locus tag: CD630_03810;  Family:  MOBT


II. ICE interaction with IME/CIME/

The interaction information of CTn1 is not available.



The graph information of CTn1 components from AM180355
Complete gene list of CTn1 from AM180355
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1CD630_03500425143..425703 [+], 561putative hydrolase, HAD superfamily
2CD630_03510425731..426222 [+], 492conserved hypothetical protein
3CD630_03520426451..427002 [+], 552Transcriptional regulator, RmlC-type
4CD630_03530427088..428020 [+], 933conserved hypothetical protein
5CD630_03540428075..457163 [+], 29089Fragment of putative membrane protein
6CD630_03541428111..428677 [+], 567putative membrane protein
7int428851..430041 [-], 1191Integrase Tn916-like, CTn1-Orf1Integrase 
8xis430119..430322 [-], 204Excisionase Tn916-like, CTn1-Orf2
9CD630_03580430695..430949 [-], 255putative conjugative transposon protein Tn916-like, CTn1-Orf3
10CD630_03590430953..431381 [-], 429putative RNA polymerase sigma factor Tn916-like, CTn1-Orf4
11CD630_03600431667..432041 [-], 375Transcriptional regulator, GntR family,Tn916-like, CTn1-Orf5
12CD630_03610432090..433091 [-], 1002Two-component sensor histidine kinase Tn916-like, CTn1-Orf6
13CD630_03620433088..433747 [-], 660Two-component response regulator Tn916-like,CTn1-Orf7
14CD630_03630433806..435782 [-], 1977ABC-type transport system, permease Tn916-like,CTn1-Orf8
15CD630_03640435772..436542 [-], 771ABC-type transport system, ATP-binding protein Tn916-like, CTn1-Orf9
16CD630_03650436715..437446 [-], 732ABC-type transport system, multidrug-family permease Tn916-like, CTn1-Orf10
17CD630_03660437439..438365 [-], 927ABC-type transport system, multidrug-family ATP-binding protein Tn916-like, CTn1-Orf11
18CD630_03670438435..439343 [-], 909Two-component sensor histidine kinase,Tn916-like, CTn1-Orf12
19CD630_03680439346..440038 [-], 693Two-component response regulator, Tn916-like,CTn1-Orf13
20CD630_03690440069..440293 [-], 225putative conjugative transposon protein Tn916-like, CTn1-Orf14
21CD630_03700440311..440511 [-], 201Transcriptional regulator, HTH-type Tn916-like,CTn1-Orf15
22CD630_03710440599..441510 [-], 912putative conjugative transposon protein Tn916-like, CTn1-Orf16Orf13_Tn, T4SS component 
23CD630_03720441526..442533 [-], 1008putative cell wall hydrolase Tn916-like,CTn1-Orf17Orf14_Tn, T4SS component 
24CD630_03730442530..444737 [-], 2208putative membrane protein Tn916-like,CTn1-Orf18Orf15_Tn, T4SS component 
25CD630_03740444737..447187 [-], 2451putative ATPase Tn916-like, CTn1-Orf19Orf16_Tn, T4SS component 
26CD630_03750447165..447563 [-], 399putative conjugative transposon protein Tn916-like, CTn1-Orf20Orf17_Tn, T4SS component 
27CD630_03760447677..448180 [-], 504putative antirestriction protein Tn916-like,CTn1-Orf21
28CD630_03770448198..448701 [-], 504putative antirestriction protein Tn916-like,CTn1-Orf22
29CD630_03780448620..448916 [-], 297putative conjugative transposon protein Tn916-like, CTn1-Orf23
30CD630_03790448992..449213 [-], 222putative conjugative transposon protein Tn916-like, CTn1-Orf24Orf19_Tn, T4SS component 
31CD630_03800449214..449348 [-], 135putative conjugative transposon protein Tn916-like, CTn1-Orf25
32CD630_03810449360..450472 [-], 1113putative replication initiation factor Tn916-like, CTn1-Orf26Relaxase, MOBT Family
33CD630_03820450811..451209 [-], 399putative conjugative transposon protein Tn916-like, CTn1-Orf27
34CD630_03830451221..452591 [-], 1371putative cell-division FtsK/SpoIIIE-family protein Tn916-like, CTn1-Orf28Orf21_Tn, T4SS component 
35CD630_03840452608..452997 [-], 390putative conjugative transposon protein DUF961 family Tn916-like, CTn1-Orf29
36CD630_03850453006..453332 [-], 327putative conjugative transposon protein DUF961 family Tn916-like, CTn1-Orf30
37CD630_03540428075..457163 [+], 29089Fragment of putative membrane protein
38CD630_03851453368..453553 [-], 186conserved hypothetical protein
39CD630_03860453566..456610 [-], 3045putative cell surface protein
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins30Fasta
(1) Sebaihia M; Wren BW; Mullany P; Fairweather NF; Minton N; Stabler R; Thomson NR; Roberts AP; Cerdeno-Tarraga AM; Wang H; Holden MT; Wright A; Churcher C; Quail MA; Baker S; Bason N; Brooks K; Chillingworth T; Cronin A; Davis P; Dowd L; Fraser A; Feltwell T; Hance Z; Holroyd S; Jagels K; Moule S; Mungall K; Price C; Rabbinowitsch E; Sharp S; Simmonds M; Stevens K; Unwin L; Whithead S; Dupuy B; Dougan G; Barrell B; Parkhill J (2006). The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 38(7):779-86. [PudMed:16804543]