ICEberg
I. Information of ICE
ICEberg ID234
Name ICESsu(SC84) This is a predicted ICE derived from literature
FamilyICESa2603
OrganismStreptococcus suis SC84
Size (bp)89165
GC content [Genome] (%)36.84[41.11]
Insertion sitethe 3' end of 50S rDNA (SSUSC84_0891)
FunctionTetracycline resistance
Species that ICE can be transferred to-
Nucleotide SequenceFM252031 (complete ICE sequence in this genome)
Replicon chromosome (2095898 bp, BioProject:32239) [NC_012924]
Genome coordinates872762..961926 
Putative oriT region -
Putative relaxase coordinates: 902177..903382; Locus tag: SSUSC84_0835;  Family:  MOBT


II. ICE interaction with IME/CIME/

The interaction information of ICESsu(SC84) is not available.



The graph information of ICESsu(SC84) components from FM252031
Complete gene list of ICESsu(SC84) from FM252031
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1SSUSC84_0803868316..869320 [-], 1005conserved hypothetical protein
2SSUSC84_0804869385..870224 [-], 840AraC family regulatory protein
3SSUSC84_0805870298..871632 [-], 1335protein Gid homolog
4SSUSC84_0806871828..872577 [-], 750haloacid dehalogenase-like hydrolase
5SSUSC84_0807872762..873961 [-], 1200tyrosine family site-specific integrase
6SSUSC84_0808873984..874211 [-], 228hypothetical protein
7SSUSC84_0809874490..874711 [-], 222transcriptional regulator, Cro/CI family
8SSUSC84_0810875041..876138 [-], 1098sensor histidine kinase
9SSUSC84_0811876123..876806 [-], 684response regulator protein
10SSUSC84_0812876837..877544 [-], 708membrane protein
11SSUSC84_0813877541..878329 [-], 789membrane protein
12SSUSC84_0814878322..879038 [-], 717putative ABC transporter ATP-binding protein
13SSUSC84_0815879059..881281 [-], 2223ABC transporter ATP-binding membrane protein
14SSUSC84_0816881285..881536 [-], 252conserved hypothetical protein
15SSUSC84_0817881548..883170 [-], 1623putative asparagine synthetase
16SSUSC84_0818883391..883519 [-], 129hypothetical protein
17SSUSC84_0819884204..886069 [-], 1866relaxase
18SSUSC84_0820886056..886421 [-], 366putative mobilisation protein
19SSUSC84_0821886421..886786 [-], 366hypothetical protein
20SSUSC84_0822887151..906351 [+], 19201putative ATP-binding protein (pseudogene)
21SSUSC84_0823888169..889386 [-], 1218integraseIntegrase 
22SSUSC84_0824889468..889671 [-], 204excisionase
23SSUSC84_0824a890132..890362 [-], 231hypothetical protein
24SSUSC84_0825890359..890781 [-], 423putative DNA-binding protein
25SSUSC84_0826891285..891638 [+], 354putative DNA-binding protein
26tetM891984..893903 [-], 1920tetracycline resistance protein TetM
27SSUSC84_0828894280..895212 [-], 933putative membrane proteinOrf13_Tn, T4SS component 
28SSUSC84_0829895209..896210 [-], 1002putative exported proteinOrf14_Tn, T4SS component 
29SSUSC84_0830896207..898384 [-], 2178putative membrane proteinOrf15_Tn, T4SS component 
30SSUSC84_0831898387..900834 [-], 2448hypothetical proteinOrf16_Tn, T4SS component 
31SSUSC84_0832900818..901324 [-], 507putative membrane proteinOrf17_Tn, T4SS component 
32SSUSC84_0833901299..901796 [-], 498antirestriction protein
33SSUSC84_0834901913..902134 [-], 222putative membrane proteinOrf19_Tn, T4SS component 
34SSUSC84_0835902177..903382 [-], 1206replication initiation factorRelaxase, MOBT Family
35SSUSC84_0836903560..904945 [-], 1386FtsK/SpoIIIE family proteinOrf21_Tn, T4SS component 
36SSUSC84_0837904974..905357 [-], 384hypothetical protein
37SSUSC84_0838905376..905690 [-], 315hypothetical protein
38SSUSC84_0839906446..908263 [-], 1818DNA helicase
39SSUSC84_0840908250..910337 [-], 2088hypothetical protein
40SSUSC84_0841910334..911110 [-], 777zeta-toxin
41SSUSC84_0842911110..911586 [-], 477antidote epsilon protein
42SSUSC84_0843911656..912009 [-], 354hypothetical protein
43SSUSC84_0844911996..912385 [-], 390hypothetical protein
44SSUSC84_0845912382..912609 [-], 228hypothetical protein
45SSUSC84_0846912663..913739 [-], 1077DNA primase
46SSUSC84_0847913778..914416 [-], 639putative exported proteinPrgL, T4SS component 
47SSUSC84_0848914923..915426 [+], 504transposase (fragment)
48salR915817..916416 [-], 600response regulator protein
49salK916394..917902 [-], 1509sensor histidine kinase
50SSUSC84_0852917906..918595 [-], 690putative membrane protein
51SSUSC84_0853918605..919324 [-], 720putative membrane protein
52SSUSC84_0854919302..920216 [-], 915lantibiotic transport ATP-binding protein
53SSUSC84_0855920188..922263 [-], 2076lantibiotic transport protein
54SSUSC84_0856922269..932752 [-], 10484lantibiotic modifying enzyme (pseudogene)
55SSUSC84_0857923753..924205 [+], 453DNA recombinase (fragment)
56SSUSC84_0858924206..924622 [+], 417Recombinase
57SSUSC84_0859924624..926186 [+], 1563DNA recombinase
58SSUSC84_0860926329..926553 [+], 225putative DNA-binding protein
59SSUSC84_0861926568..927437 [+], 870hypothetical protein
60SSUSC84_0862927418..928152 [+], 735putative methyltransferase
61aadE928185..929048 [+], 864streptomycin adenylyltransferase
62SSUSC84_0864929092..929619 [+], 528putative adenine phosphoribosyltransferase
63SSUSC84_0865929847..931166 [+], 1320putative transposase
64SSUSC84_0866932836..933009 [-], 174lantibiotic precursor
65SSUSC84_0868933350..933646 [-], 297putative membrane protein
66SSUSC84_0869933660..933959 [-], 300hypothetical protein
67SSUSC84_0870934030..940854 [-], 6825hypothetical protein
68SSUSC84_0871940904..941455 [-], 552hypothetical protein
69SSUSC84_0872941439..941630 [-], 192hypothetical protein
70SSUSC84_0873941631..946526 [-], 4896putative glucan-binding surface-anchored proteinPrgB, T4SS component 
71SSUSC84_0874946698..947288 [+], 591hypothetical protein
72SSUSC84_0875947285..948130 [+], 846hypothetical protein
73SSUSC84_0876948193..950994 [-], 2802hypothetical proteinPrgK, T4SS component 
74SSUSC84_0877950996..953326 [-], 2331hypothetical proteinPrgJ, T4SS component 
75SSUSC84_0878953304..953657 [-], 354putative membrane protein
76SSUSC84_0879953719..954573 [-], 855putative TrbL/VirB6 plasmid conjugal transfer protein
77SSUSC84_0880954592..954834 [-], 243putative membrane protein
78SSUSC84_0881954852..956669 [-], 1818putative conjugal transfer protein TraG
79SSUSC84_0882956669..957157 [-], 489hypothetical protein
80SSUSC84_0883957235..957819 [-], 585CAAX amino terminal protease family protein
81SSUSC84_0884957822..958055 [-], 234hypothetical protein
82SSUSC84_0885958064..958447 [-], 384hypothetical protein
83SSUSC84_0886958458..958886 [-], 429hypothetical protein
84SSUSC84_0887958870..960225 [-], 1356C-5 cytosine-specific DNA methylase
85SSUSC84_0889960374..961192 [-], 819replication initiator protein A protein
86SSUSC84_0890961189..961362 [-], 174hypothetical protein
87rplL961561..961926 [-], 36650S ribosomal protein L7/L12
88rplJ961992..962486 [-], 49550S ribosomal protein L10
89topA963063..965156 [-], 2094DNA topoisomerase I
90SSUSC84_0894965249..966091 [-], 843SMF family protein
91maa966150..966707 [-], 558maltose O-acetyltransferase
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins79Fasta
(1) Palmieri C; Varaldo PE; Facinelli B (2011). Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. Front Microbiol. 0.246527778. [PudMed:22275909]
(2) Holden MT; Hauser H; Sanders M; Ngo TH; Cherevach I; Cronin A; Goodhead I; Mungall K; Quail MA; Price C; Rabbinowitsch E; Sharp S; Croucher NJ; Chieu TB; Mai NT; Diep TS; Chinh NT; Kehoe M; Leigh JA; Ward PN; Dowson CG; Whatmore AM; Chanter N; Iversen P; Gottschalk M; Slater JD; Smith HE; Spratt BG; Xu J; Ye C; Bentley S; Barrell BG; Schultsz C; Maskell DJ; Parkhill J (2009). Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One. 4(7):e6072. [PudMed:19603075]