ICEberg
I. Information of ICE
ICEberg ID233
Name ICESsu(BM407)2 This is a predicted ICE derived from literature
FamilyICESa2603
OrganismStreptococcus suis BM407
Size (bp)80320
GC content [Genome] (%)37.11[41.06]
Insertion sitethe 3' end of 50S rDNA (SSUBM407_0933)
FunctionTetracycline and streptomycin resistance
Species that ICE can be transferred to-
Nucleotide SequenceFM252032 (complete ICE sequence in this genome)
Replicon chromosome (2146229 bp, BioProject:32237) [NC_012926]
Genome coordinates1005794..1086113 
Putative oriT region -
Putative relaxase coordinates: 1068244..1069506; Locus tag: SSUBM407_0973;  Family:  MOBV


II. ICE interaction with IME/CIME/

The interaction information of ICESsu(BM407)2 is not available.



The graph information of ICESsu(BM407)2 components from FM252032
Complete gene list of ICESsu(BM407)2 from FM252032
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1SSUBM407_09301001264..1002106 [+], 843SMF family protein
2topA1002199..1004292 [+], 2094DNA topoisomerase I
3rplJ1004869..1005363 [+], 49550S ribosomal protein L10
4rplL1005429..1005794 [+], 36650S ribosomal protein L7/L12
5SSUBM407_0933a1005993..1006166 [+], 174hypothetical protein
6SSUBM407_09341006163..1006981 [+], 819replication initiator protein A protein
7SSUBM407_09351007130..1008485 [+], 1356C-5 cytosine-specific DNA methylase
8SSUBM407_09361008469..1008897 [+], 429hypothetical protein
9SSUBM407_09371008908..1009291 [+], 384hypothetical protein
10SSUBM407_09381009300..1009533 [+], 234hypothetical protein
11SSUBM407_09391009536..1010120 [+], 585CAAX amino terminal protease family protein
12SSUBM407_09401010198..1010686 [+], 489hypothetical protein
13SSUBM407_09411010686..1012503 [+], 1818putative conjugal transfer protein TraG
14SSUBM407_09421012521..1012763 [+], 243putative membrane protein
15SSUBM407_09431012782..1013636 [+], 855putative TrbL/VirB6 plasmid conjugal transfer protein
16SSUBM407_09441013698..1014051 [+], 354putative membrane protein
17SSUBM407_09451014029..1016359 [+], 2331hypothetical proteinPrgJ, T4SS component 
18SSUBM407_09461016361..1019162 [+], 2802hypothetical proteinPrgK, T4SS component 
19SSUBM407_09471019224..1020069 [-], 846hypothetical protein
20SSUBM407_09481020066..1020656 [-], 591hypothetical protein
21SSUBM407_09491020937..1025832 [+], 4896putative glucan-binding surface-anchored proteinPrgB, T4SS component 
22SSUBM407_0949a1025833..1026024 [+], 192hypothetical protein
23SSUBM407_09501026008..1026559 [+], 552hypothetical protein
24SSUBM407_09511026609..1030454 [+], 3846hypothetical protein (fragment)
25SSUBM407_0951a1030458..1030832 [+], 375hypothetical protein (fragment)
26ermB1031089..1031826 [+], 738rRNA adenine N-6-methyltransferase
27SSUBM407_09531032298..1032672 [+], 375hypothetical protein
28tetO1033039..1034958 [+], 1920tetracycline resistance protein TetO
29SSUBM407_0954a1035250..1035327 [-], 78putative adenine phosphoribosyltransferase (fragment)
30aadE1035371..1036234 [-], 864streptomycin adenylyltransferase
31SSUBM407_09561036267..1036950 [-], 684putative methyltransferase
32SSUBM407_09571037077..1037550 [-], 474dihydrofolate reductase
33SSUBM407_09581037653..1038678 [-], 1026putative transposase
34SSUBM407_09591038786..1039655 [-], 870hypothetical protein
35SSUBM407_09601039670..1039894 [-], 225putative DNA-binding protein
36SSUBM407_0960a1040037..1040117 [-], 81DNA recombinase (fragment)
37SSUBM407_0960b1040118..1040168 [+], 51putative membrane protein (fragment)
38SSUBM407_0960c1040172..1040201 [+], 30two-component sensor histidine kinase (fragment)
39SSUBM407_0961a1040599..1041102 [-], 504transposase (fragment)
40SSUBM407_09611041609..1042247 [+], 639putative exported proteinPrgL, T4SS component 
41SSUBM407_09621042286..1043362 [+], 1077DNA primase
42SSUBM407_09631043416..1043643 [+], 228hypothetical protein
43SSUBM407_09641043640..1044029 [+], 390hypothetical protein
44SSUBM407_09651044016..1044369 [+], 354hypothetical protein
45SSUBM407_09661044439..1044915 [+], 477antidote epsilon protein
46SSUBM407_09671044915..1045691 [+], 777zeta-toxin
47SSUBM407_09681045688..1047775 [+], 2088hypothetical protein
48SSUBM407_09691047762..1049579 [+], 1818DNA helicase
49SSUBM407_09901049673..1074215 [-], 24543putative ATP-binding protein (pseudogene)
50SSUBM407_09701050335..1050649 [+], 315hypothetical protein
51SSUBM407_09711050665..1051051 [+], 387hypothetical protein
52SSUBM407_09721051080..1052462 [+], 1383FtsK/SpoIIIE family proteinOrf21_Tn, T4SS component 
53SSUBM407_09731052641..1053846 [+], 1206replication initiation factorRelaxase, MOBT Family
54SSUBM407_09741053889..1054110 [+], 222putative membrane proteinOrf19_Tn, T4SS component 
55SSUBM407_09751054227..1054724 [+], 498antirestriction protein
56SSUBM407_09761054699..1055205 [+], 507putative membrane proteinOrf17_Tn, T4SS component 
57SSUBM407_09771055189..1057636 [+], 2448hypothetical proteinOrf16_Tn, T4SS component 
58SSUBM407_09781057639..1061887 [+], 4249putative membrane protein (pseudogene)
59SSUBM407_09791059554..1060600 [+], 1047putative transposase
60cat1060737..1061360 [+], 624chloramphenicol acetyltransferase
61SSUBM407_09811061884..1062885 [+], 1002putative exported proteinOrf14_Tn, T4SS component 
62SSUBM407_09821062882..1063814 [+], 933putative membrane proteinOrf13_Tn, T4SS component 
63tetM21064191..1066110 [+], 1920tetracycline resistance protein TetM 2
64tetL1066304..1067680 [+], 1377tetracycline resistance protein TetL
65pre1068244..1069506 [+], 1263plasmid recombination enzyme type 2Relaxase, MOBV Family
66SSUBM407_09861069781..1070080 [-], 300putative DNA-binding protein (fragment)
67SSUBM407_09871070585..1071007 [+], 423putative DNA-binding protein
68SSUBM407_0987a1071004..1071234 [+], 231hypothetical protein
69SSUBM407_09881071695..1071898 [+], 204excisionase
70SSUBM407_09891071980..1073197 [+], 1218integraseIntegrase 
71SSUBM407_09911074580..1074945 [+], 366hypothetical protein
72SSUBM407_09921074945..1075310 [+], 366putative mobilisation protein
73SSUBM407_09931075297..1077162 [+], 1866relaxase
74SSUBM407_09951077725..1079824 [+], 2100ABC transporter ATP-binding membrane protein
75SSUBM407_09961079837..1080553 [+], 717putative ABC transporter ATP-binding protein
76SSUBM407_09971080546..1081334 [+], 789membrane protein
77SSUBM407_09981081331..1082038 [+], 708membrane protein
78SSUBM407_09991082069..1082752 [+], 684response regulator protein
79SSUBM407_10001082737..1083834 [+], 1098sensor histidine kinase
80SSUBM407_10011084164..1084385 [+], 222transcriptional regulator, Cro/CI family
81SSUBM407_10021084664..1084891 [+], 228hypothetical protein
82SSUBM407_10031084914..1086113 [+], 1200tyrosine family site-specific integrase
83SSUBM407_10041086298..1087047 [+], 750haloacid dehalogenase-like hydrolase
84SSUBM407_10051087243..1088577 [+], 1335protein Gid homolog
85SSUBM407_10061088651..1089490 [+], 840AraC family regulatory protein
86SSUBM407_10071089555..1090559 [+], 1005conserved hypothetical protein
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins68Fasta
(1) Palmieri C; Varaldo PE; Facinelli B (2011). Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. Front Microbiol. 0.246527778. [PudMed:22275909]
(2) Holden MT; Hauser H; Sanders M; Ngo TH; Cherevach I; Cronin A; Goodhead I; Mungall K; Quail MA; Price C; Rabbinowitsch E; Sharp S; Croucher NJ; Chieu TB; Mai NT; Diep TS; Chinh NT; Kehoe M; Leigh JA; Ward PN; Dowson CG; Whatmore AM; Chanter N; Iversen P; Gottschalk M; Slater JD; Smith HE; Spratt BG; Xu J; Ye C; Bentley S; Barrell BG; Schultsz C; Maskell DJ; Parkhill J (2009). Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One. 4(7):e6072. [PudMed:19603075]