ICEberg
I. Information of ICE
ICEberg ID230
Name ICESp23FST81 This is a predicted ICE derived from literature
FamilyTn5253
OrganismStreptococcus pneumoniae ATCC 700669
Size (bp)81016
GC content [Genome] (%)34.26[39.49]
Insertion sitethe 3' end of rplL (SPN23F_13190)
FunctionTetracycline and chloramphenicol resistance; Toxin-antitoxin system
Species that ICE can be transferred to-
Nucleotide SequenceFM211187 (complete ICE sequence in this genome)
Replicon chromosome (2221315 bp, BioProject:31233) [NC_011900]
Genome coordinates1207785..1288800 
Putative oriT region -
Putative relaxase coordinates: 1269128..1270333; Locus tag: SPN23F12970;  Family:  MOBT


II. ICE interaction with IME/CIME/

The interaction information of ICESp23FST81 is not available.



The graph information of ICESp23FST81 components from FM211187
Complete gene list of ICESp23FST81 from FM211187
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1SPN23F123401205229..1205366 [-], 138putative uncharacterized protein
2SPN23F123501205568..1206155 [-], 588putative membrane protein
3SPN23F123601206158..1206391 [-], 234putative uncharacterized protein (pseudogene)
4SPN23F123701206404..1206784 [-], 381putative uncharacterized protein
5SPN23F123801206777..1207100 [-], 324putative uncharacterized protein
6SPN23F123901207108..1207362 [-], 255putative replication initiator protein
7SPN23F124001207362..1207532 [-], 171conserved hypothetical protein
8SPN23F124101207785..1208972 [-], 1188integraseIntegrase 
9SPN23F124201208944..1209213 [-], 270conserved hypothetical protein
10SPN23F124301209814..1211643 [-], 1830relaxase
11SPN23F124401211630..1211995 [-], 366putative mobilisation protein
12SPN23F124501212000..1212356 [-], 357putative mobilisation protein
13SPN23F124601212740..1212994 [-], 255putative uncharacterized protein
14SPN23F124701213060..1217064 [-], 4005putative DNA helicase II, UvrD
15SPN23F124801217186..1217572 [-], 387hypothetical protein
16SPN23F124901217644..1218594 [-], 951putative uncharacterized protein
17SPN23F125001218679..1219797 [-], 1119putative uncharacterized protein
18SPN23F125101220059..1221855 [-], 1797putative NTPase protein
19SPN23F125201222272..1222538 [-], 267hypothetical protein
20SPN23F125301222525..1223229 [-], 705putative phosphoserine phosphatase
21SPN23F125401223282..1223848 [-], 567hypothetical protein
22SPN23F125501223941..1224165 [-], 225hypothetical protein
23SPN23F125601224254..1224871 [-], 618hypothetical protein
24SPN23F125701225193..1225915 [-], 723putative uncharacterized protein
25rep1226244..1227167 [+], 924replication protein
26SPN23F125901228032..1228682 [-], 651putative chloramphenicol acetyltransferase
27SPN23F126001228853..1229101 [-], 249putative uncharacterized protein
28SPN23F126101229340..1230128 [-], 789putative uncharacterized protein
29SPN23F126201230604..1231362 [-], 759zeta toxin
30SPN23F126301231362..1231838 [-], 477putative epsilon antitoxin
31SPN23F126401231908..1232180 [-], 273putative uncharacterized protein
32SPN23F126501232218..1232601 [-], 384putative uncharacterized protein
33SPN23F126601232598..1232831 [-], 234putative uncharacterized protein
34SPN23F126701232882..1233967 [-], 1086putative uncharacterized protein
35SPN23F126801233977..1234618 [-], 642putative uncharacterized proteinPrgL, T4SS component 
36SPN23F126901234839..1236962 [-], 2124putative lantibiotic transport/processing ATP-binding protein
37SPN23F127001236969..1240220 [-], 3252putative lantibiotic synthetase
38SPN23F127011240303..1240518 [-], 216putative lantibiotic precursor
39SPN23F127101240663..1241343 [-], 681putative lantibiotic ABC transporter
40SPN23F127201241392..1242132 [-], 741putative lantibiotic ABC transporter
41SPN23F127301242125..1243060 [-], 936putative lantibiotic ABC transporter, ATP-binding protein
42SPN23F127401243238..1243411 [-], 174putative membrane protein
43SPN23F127501243602..1244462 [+], 861transcriptional regulator
44SPN23F127601244545..1244835 [-], 291putative membrane protein
45SPN23F127701244849..1245133 [-], 285putative uncharacterized protein
46SPN23F127801245208..1253932 [-], 8725putative conjugative transposon DNA recombination protein
47SPN23F127901246260..1248071 [-], 1812putative group II intron reverse transcriptase/maturase
48SPN23F128201253980..1254390 [-], 411putative uncharacterized protein (pseudogene)
49SPN23F128301254542..1255108 [-], 567putative uncharacterized protein
50SPN23F128401255346..1258159 [-], 2814putative conjugal transfer proteinPrgK, T4SS component 
51SPN23F128501258171..1260486 [-], 2316putative conjugal transfer proteinPrgJ, T4SS component 
52SPN23F128601260476..1260838 [-], 363putative uncharacterized protein
53SPN23F128701260892..1261746 [-], 855putative uncharacterized proteinPrgH, T4SS component 
54SPN23F128801261763..1262005 [-], 243putative uncharacterized protein
55traG1262026..1263906 [-], 1881putative conjugal transfer protein TraG
56SPN23F129001263903..1264391 [-], 489putative uncharacterized protein
57SPN23F129101264381..1264680 [-], 300putative uncharacterized protein
58SPN23F129201264963..1265799 [-], 837conserved hypothetical protein
59SPN23F129301265799..1266389 [-], 591conserved hypothetical protein
60orf231266820..1267134 [+], 315conjugative transposon protein
61orf221267153..1267536 [+], 384conjugative transposon protein
62orf211267565..1268950 [+], 1386conjugative transposon FtsK/SpoIIIE-family proteinOrf21_Tn, T4SS component 
63orf201269128..1270333 [+], 1206putative conjugative transposon replication initiation factorRelaxase, MOBT Family
64orf191270376..1270597 [+], 222conjugative transposon proteinOrf19_Tn, T4SS component 
65orf181270714..1271211 [+], 498conjugative transposon protein
66orf171271462..1271692 [+], 231putative conjugative transposon membrane proteinOrf17_Tn, T4SS component 
67orf161271676..1274123 [+], 2448conjugative transposon ATP/GTP-binding proteinOrf16_Tn, T4SS component 
68orf151274126..1276276 [+], 2151conjugative transposon membrane proteinOrf15_Tn, T4SS component 
69orf141276295..1277296 [+], 1002putative cell wall hydrolaseOrf14_Tn, T4SS component 
70orf131277311..1278225 [+], 915putative conjugative transposon exported proteinOrf13_Tn, T4SS component 
71tetM1278602..1280521 [+], 1920conjugative transposon tetracycline resistance protein
72orf91280867..1281220 [-], 354putative conjugative transposon regulatory protein
73SPN23F130611281350..1281496 [+], 147putative uncharacterized protein
74orf71281725..1282147 [+], 423putative conjugative transposon regulatory protein
75xis1282835..1283038 [+], 204excisionase
76SPN23F130901283120..1284336 [+], 1217putative integrase (pseudogene)
77SPN23F131101284551..1285138 [-], 588putative CAAX amino terminal protease
78SPN23F131201285141..1285374 [-], 234putative uncharacterized protein
79SPN23F131301285387..1285767 [-], 381putative uncharacterized protein
80SPN23F131401285760..1286209 [-], 450putative uncharacterized protein
81SPN23F131501286193..1287551 [-], 1359putative DNA methylase
82SPN23F131601287650..1288429 [-], 780putative replication initiator protein
83SPN23F131701288426..1288599 [-], 174putative uncharacterized protein
84rplL1288801..1289169 [-], 36950S ribosomal protein L7/L12
85rplJ1289245..1289745 [-], 50150S ribosomal protein L10
86SPN23F132101289995..1291254 [-], 1260probable amidohydrolase
87SPN23F132201291601..1293349 [-], 1749ABC transporter ATP-binding membrane protein
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins74Fasta
(1) Croucher NJ; Walker D; Romero P; Lennard N; Paterson GK; Bason NC; Mitchell AM; Quail MA; Andrew PW; Parkhill J; Bentley SD; Mitchell TJ (2009). Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniaeSpain23F ST81. J Bacteriol. 191(5):1480-9. [PudMed:19114491]