ICEberg
I. Information of ICE
ICEberg ID190
Name 10270-RD.1 This is a predicted ICE derived from literature
Family10270-RD.1
OrganismStreptococcus pyogenes MGAS10270
Size (bp)15367
GC content [Genome] (%)30.99[38.43]
Insertion site-
FunctionSrtA required for cell wall anchoring of protein A as well as virulence
Species that ICE can be transferred to-
Nucleotide SequenceCP000260 (complete ICE sequence in this genome)
Replicon chromosome (1928252 bp, BioProject:16364) [NC_008022]
Genome coordinates871808..887174 
Putative oriT region -
Putative relaxase coordinates: 872871..873083; Locus tag: MGAS10270_Spy0914;  Family:  MOBP


II. ICE interaction with IME/CIME/

The interaction information of 10270-RD.1 is not available.



The graph information of 10270-RD.1 components from CP000260
Complete gene list of 10270-RD.1 from CP000260
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1MGAS10270_Spy0906867243..868703 [+], 1461Xaa-His dipeptidase
2thdF868771..870147 [-], 1377tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
3rplJ870419..870982 [+], 564LSU ribosomal protein L10P
4rplL871032..871412 [+], 381LSU ribosomal protein L12P (L7/L12)
5MGAS10270_Spy0910871808..871948 [+], 141hypothetical protein
6MGAS10270_Spy0911871942..872310 [+], 369hypothetical protein
7MGAS10270_Spy0912872327..872431 [+], 105hypothetical protein
8MGAS10270_Spy0913872481..872813 [+], 333DNA-cytosine methyltransferase
9MGAS10270_Spy0914872871..873083 [+], 213RelaxaseRelaxase, MOBP Family
10MGAS10270_Spy0915873126..873338 [+], 213Relaxase
11srtI873604..874299 [+], 696Relaxase
12srtR874450..875136 [+], 687Lantibiotic biosynthesis two-component response regulator
13srtK875114..876475 [+], 1362Lantibiotic biosynthesis sensor protein
14srtA876632..876772 [+], 141Lantibiotic srtA precursor
15srtT876887..878677 [+], 1791Lantibiotic transport permease protein / Lantibiotic transport ATP-binding protein
16MGAS10270_Spy0921878649..879905 [+], 1257Lanthionine synthetase
17MGAS10270_Spy0922879924..882890 [+], 2967serine/threoninedehydratase
18srtF882839..883585 [+], 747Lantibiotic transport ATP-binding protein
19srtE883591..884340 [+], 750Lantibiotic transport permease protein
20srtG884343..885065 [+], 723Lantibiotic transport permease protein
21MGAS10270_Spy0926885257..885424 [+], 168Transcriptional regulator, Cro/CI family
22MGAS10270_Spy0928885571..885873 [-], 303hypothetical protein
23MGAS10270_Spy0927885760..885984 [+], 225hypothetical protein
24MGAS10270_Spy0929885987..886118 [+], 132DNA integration/recombination/inversion protein
25MGAS10270_Spy0930886140..886361 [+], 222DNA integration/recombination/inversion protein
26MGAS10270_Spy0931886434..886655 [+], 222DNA integration/recombination/inversion protein
27MGAS10270_Spy0932886686..887174 [+], 489DNA integration/recombination/inversion proteinIntegrase 
28dacA1887212..888567 [+], 1356D-alanyl-D-alanine serine-type carboxypeptidase
29MGAS10270_Spy0934888683..889645 [-], 963Polysaccharide deacetylase
30MGAS10270_Spy0935889733..889888 [+], 156hypothetical protein
31folC1889878..891254 [+], 1377Folylpolyglutamate synthase / Dihydrofolate synthase
32folE891265..891873 [+], 609GTP cyclohydrolase I
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins23Fasta
(1) Beres SB; Musser JM (2007). Contribution of exogenous genetic elements to the group A Streptococcus metagenome. PLoS One. 2(8):e800. [PudMed:17726530]