ICEberg
I. Information of ICE
ICEberg ID189
Name 5005-RD.1 This is a predicted ICE derived from literature
Family10270-RD.1
OrganismStreptococcus pyogenes MGAS5005
Size (bp)9916
GC content [Genome] (%)32.07[38.53]
Insertion site-
FunctionSrtA required for cell wall anchoring of protein A as well as virulence
Species that ICE can be transferred to-
Nucleotide SequenceCP000017 (complete ICE sequence in this genome)
Replicon chromosome (1838554 bp, BioProject:13888) [NC_007297]
Genome coordinates802286..812201 
Putative oriT region -
Putative relaxase -


II. ICE interaction with IME/CIME/

The interaction information of 5005-RD.1 is not available.



The graph information of 5005-RD.1 components from CP000017
Complete gene list of 5005-RD.1 from CP000017
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1M5005_Spy0793797774..799183 [+], 1410Xaa-His dipeptidase
2thdF799251..800627 [-], 1377tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
3rplJ800864..801460 [+], 597LSU ribosomal protein L10P
4rplL801525..801890 [+], 366LSU ribosomal protein L12P
5M5005_Spy0797802286..802426 [+], 141hypothetical protein
6M5005_Spy0798802420..802788 [+], 369IFN-response binding factor 1
7M5005_Spy0799802767..802904 [+], 138hypothetical protein
8M5005_Spy0800802963..803286 [+], 324DNA-cytosine methyltransferase
9M5005_Spy0801803344..803466 [+], 123relaxase
10M5005_Spy0802803599..803811 [+], 213relaxase
11srtI804076..804771 [+], 696protein involved in lantibiotic production
12srtR804922..805608 [+], 687nisin biosynthesis two-component response regulator
13srtK805601..806947 [+], 1347nisin biosynthesis sensor protein
14srtA807095..807235 [+], 141lantibiotic precursor
15srtT807350..807967 [+], 618ABC transporter (ATP binding)-lantibiotic associated
16srtF808049..808738 [+], 690lantibiotic transport ATP-binding protein
17srtE808744..809493 [+], 750lantibiotic transport permease protein
18srtG809496..810218 [+], 723lantibiotic transport permease protein
19M5005_Spy0811810410..810628 [+], 219transcriptional regulator, Cro/CI family
20M5005_Spy0812810737..810952 [-], 216hypothetical protein
21M5005_Spy0813811119..811250 [+], 132integrase pseudogene
22M5005_Spy0814811272..811493 [+], 222integrase pseudogene
23M5005_Spy0815811566..811787 [+], 222integrase pseudogene
24M5005_Spy0816811818..812201 [+], 384integrase pseudogeneIntegrase 
25dacA1812371..813699 [+], 1329D-alanyl-D-alanine carboxypeptidase
26M5005_Spy0818813816..814778 [-], 963polysaccharide deacetylase
27M5005_Spy0819814866..815021 [+], 156hypothetical protein
28folC.1815110..816387 [+], 1278folylpolyglutamate synthase/dihydrofolate synthase
29folE816434..817000 [+], 567GTP cyclohydrolase I
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins20Fasta
(1) Beres SB; Musser JM (2007). Contribution of exogenous genetic elements to the group A Streptococcus metagenome. PLoS One. 2(8):e800. [PudMed:17726530]