ICEberg
I. Information of ICE
ICEberg ID182
Name 10750-RD.1 This is a predicted ICE derived from literature
Family10270-RD.1
OrganismStreptococcus pyogenes MGAS10750
Size (bp)15415
GC content [Genome] (%)31[38.32]
Insertion site-
FunctionSrtA required for cell wall anchoring of protein A as well as virulence
Species that ICE can be transferred to-
Nucleotide SequenceCP000262 (complete ICE sequence in this genome)
Replicon chromosome (1937111 bp, BioProject:16366) [NC_008024]
Genome coordinates902811..918225 
Putative oriT region -
Putative relaxase coordinates: 903897..904109; Locus tag: MGAS10750_Spy0949;  Family:  MOBP


II. ICE interaction with IME/CIME/

The interaction information of 10750-RD.1 is not available.



The graph information of 10750-RD.1 components from CP000262
Complete gene list of 10750-RD.1 from CP000262
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1MGAS10750_Spy0941898246..899706 [+], 1461Xaa-His dipeptidase
2thdF899774..901150 [-], 1377tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
3rplJ901423..901986 [+], 564LSU ribosomal protein L10P
4rplL902036..902416 [+], 381LSU ribosomal protein L12P (L7/L12)
5MGAS10750_Spy0945902811..902972 [+], 162hypothetical protein
6MGAS10750_Spy0946902966..903334 [+], 369hypothetical protein
7MGAS10750_Spy0947903351..903455 [+], 105hypothetical protein
8MGAS10750_Spy0948903505..903864 [+], 360DNA-cytosine methyltransferase
9MGAS10750_Spy0949903897..904109 [+], 213RelaxaseRelaxase, MOBP Family
10MGAS10750_Spy0950904152..904364 [+], 213Relaxase
11MGAS10750_Spy0951904629..904940 [+], 312Relaxase
12srtI905009..905326 [+], 318Relaxase
13srtR905477..906163 [+], 687Lantibiotic biosynthesis two-component response regulator
14srtK906141..907502 [+], 1362Lantibiotic biosynthesis sensor protein
15srtA907659..907799 [+], 141Lantibiotic srtA precursor
16srtT907914..909704 [+], 1791Lantibiotic transport permease protein / Lantibiotic transport ATP-binding protein
17MGAS10750_Spy0957909676..910932 [+], 1257Lanthionine synthetase
18MGAS10750_Spy0958910951..913917 [+], 2967serine/threoninedehydratase
19srtF913866..914612 [+], 747Lantibiotic transport ATP-binding protein
20srtE914618..915367 [+], 750Lantibiotic transport permease protein
21srtG915370..916092 [+], 723Lantibiotic transport permease protein
22MGAS10750_Spy0962916284..916502 [+], 219Transcriptional regulator, Cro/CI family
23MGAS10750_Spy0964916611..916913 [-], 303hypothetical protein
24MGAS10750_Spy0963916800..917024 [+], 225hypothetical protein
25MGAS10750_Spy0965917027..917158 [+], 132DNA integration/recombination/inversion protein
26MGAS10750_Spy0966917485..917706 [+], 222DNA integration/recombination/inversion protein
27MGAS10750_Spy0967917737..918225 [+], 489DNA integration/recombination/inversion proteinIntegrase 
28dacA1918263..919618 [+], 1356D-alanyl-D-alanine serine-type carboxypeptidase
29MGAS10750_Spy0969919735..920697 [-], 963Polysaccharide deacetylase
30MGAS10750_Spy0970920785..920940 [+], 156hypothetical protein
31folC1920930..922306 [+], 1377Folylpolyglutamate synthase / Dihydrofolate synthase
32folE922317..922919 [+], 603GTP cyclohydrolase I
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins23Fasta
(1) Beres SB; Musser JM (2007). Contribution of exogenous genetic elements to the group A Streptococcus metagenome. PLoS One. 2(8):e800. [PudMed:17726530]