ICEberg
I. Information of ICE
ICEberg ID163
Name SLP1 {AICE} This ICE is derived from experimental literature
FamilyUnclassified
OrganismStreptomyces coelicolor A3(2)
Size (bp)17204
GC content [Genome] (%)67.94[72.12]
Insertion sitetRNA-Tyr
FunctionCleavage of phosphorothioated DNA and methylated DNA by the type IV restriction endonuclease ScoMcrA
Species that ICE can be transferred toStreptomyces lividans
Nucleotide SequenceNC_003888 (complete ICE sequence in this genome)
Replicon chromosome (8667507 bp, BioProject:242) [NC_003888]
Genome coordinates5038594..5055797 
Putative oriT region -
Putative relaxase -


II. ICE interaction with IME/CIME/

The interaction information of SLP1 {AICE} is not available.



The graph information of SLP1 {AICE} components from NC_003888
Complete gene list of SLP1 {AICE} from NC_003888
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1SCO46095033984..5034847 [+], 864heat shock protein HtpX
2SCO46105034844..5035260 [+], 417hypothetical protein
3SCO46115035358..5035951 [+], 594hypothetical protein
4SCO46125036030..5037274 [-], 1245amino acid transporter
5SCO46135037414..5037680 [+], 267integral membrane protein
6SCO46145037788..5038276 [-], 489putative nucleotide-binding protein
7SCO46155038758..5040125 [-], 1368integraseIntegrase 
8SCO46165040186..5040371 [-], 186excisionase
9SCO46175040809..5042281 [-], 1473ATP-binding protein
10SCO46185042283..5043134 [-], 852hypothetical protein
11SCO46195043224..5043691 [-], 468integral membrane protein
12SCO46205043865..5045910 [-], 2046sporulation-related proteinT4CP 
13SCO46215045925..5046464 [-], 540sporulation-related protein
14SCO46225046484..5046984 [-], 501integral membrane protein
15SCO46235047012..5047170 [+], 159hypothetical protein
16SCO46245047328..5047663 [-], 336hypothetical protein
17SCO46255047663..5048670 [-], 1008hypothetical protein
18SCO46265048667..5049200 [-], 534hypothetical protein
19SCO46275049197..5049466 [-], 270hypothetical protein
20SCO46285049893..5050702 [+], 810regulator
21SCO46295050699..5051364 [+], 666hypothetical protein
22SCO46305051465..5052724 [-], 1260hypothetical protein
23ScoMcrA(SCO4631)5052984..5054666 [-], 1683type IV restriction endonuclease ScoMcrA
24SCO46325055828..5058728 [+], 2901ATP/GTP binding protein
25SCO46335059025..5059681 [-], 657hypothetical protein
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins17Fasta
(1) Liu G; Ou HY; Wang T; Li L; Tan H; Zhou X; Rajakumar K; Deng Z; He X (2010). Cleavage of phosphorothioated DNA and methylated DNA by the type IV restriction endonuclease ScoMcrA. PLoS Genet. 6(12):e1001253. [PudMed:21203499] experimental
(2) Brasch MA; Pettis GS; Lee SC; Cohen SN (1993). Localization and nucleotide sequences of genes mediating site-specific recombination of the SLP1 element in Streptomyces lividans. J Bacteriol. 175(10):3067-74. [PudMed:8387993] experimental
(3) Bibb MJ; Ward JM; Kieser T; Cohen SN; Hopwood DA (1981). Excision of chromosomal DNA sequences from Streptomyces coelicolor forms a novel family of plasmids detectable in Streptomyces lividans. Mol Gen Genet. 184(2):230-40. [PudMed:6948998] experimental
(4) Omer CA; Cohen SN (1984). Plasmid formation in Streptomyces: excision and integration of the SLP1 replicon at a specific chromosomal site. Mol Gen Genet. 196(3):429-38. [PudMed:6094971] experimental
(5) Lee SC; Omer CA; Brasch MA; Cohen SN (1988). Analysis of recombination occurring at SLP1 att sites. J Bacteriol. 170(12):5806-13. [PudMed:3056916] experimental
(6) Vogtli M; Cohen SN (1992). The chromosomal integration site for the Streptomyces plasmid SLP1 is a functional tRNA(Tyr) gene essential for cell viability. Mol Microbiol. 6(20):3041-50. [PudMed:1479893] experimental
 
experimental experimental literature