ICEberg
I. Information of ICE
ICEberg ID1010
Name ICEPae690 This ICE is derived from experimental literature
FamilyICEclc
OrganismPseudomonas aeruginosa
Size (bp)86203
GC content [Genome] (%)63.05
Insertion sitetRNAGly
FunctionblaOXA-48
Species that ICE can be transferred toPseudomonas aeruginosa
Nucleotide SequenceKY852375 (complete ICE sequence in this GenBank file)
Replicon-
Coordinates315..86517 
Putative oriT region -
Putative relaxase coordinates: 35328..37166;   Family:  MOBH


II. ICE interaction with IME/CIME/

The interaction information of ICEPae690 is not available.



The graph information of ICEPae690 components from KY852375
Complete gene list of ICEPae690 from KY852375
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
*Reannotation 
1-541..2484 [+], 1944Integrase
2-2522..3490 [-], 969putative peroxidase
3-3609..4346 [-], 738LysR family transcriptional regulator
4-4358..4753 [-], 396DNA-binding protein
5-4750..5001 [-], 252toxin-antitoxin system, antitoxin component, AbrB family
6-5183..5749 [+], 567Invertase
7-6097..7110 [-], 1014IntI1 class I integraseIntegrase 
8-7293..8156 [+], 864Carbapenem-hydrolyzing class A beta-lactamase GES-6AR 
9-8280..8738 [+], 459Aminoglycoside N-acetyltransferase AAC(6')-Il
10-9113..10210 [-], 1098Transposase of ISPa55
11-10512..10859 [+], 348QacEdelta1 multidrug efflux protein
12-10853..11692 [+], 840Sul1 sulfonamide-resistant dihydropteroate synthaseAR 
13-11724..12320 [+], 597Orf5 acetyltransferase
14-12656..12949 [+], 294Transcriptional regulator
15-12972..13862 [-], 891LysR family transcriptional regulator
16-14366..15580 [-], 1215Aldehyde dismutase
17-16047..16988 [-], 942LysR family transcriptional regulator
18-17481..17912 [+], 432hypothetical protein
19-18287..20263 [+], 1977Excinuclease ABC subunit B
20-20414..21319 [-], 906LysR family transcriptional regulator
21-21474..21881 [+], 408Isopropylmalate/homocitrate/citramalate synthase
22-21883..22491 [+], 609hypothetical protein
23-22488..23378 [+], 891Nitrilase
24-23661..23936 [+], 276Regulator
25-23996..25105 [+], 1110S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase
26-25149..25547 [+], 399Glyoxalase
27-25730..27064 [+], 1335hypothetical protein
28-27123..27953 [+], 831S-formylglutathione hydrolase
29-27972..29279 [+], 1308NADH dehydrogenase
30-29331..30644 [+], 1314Recombination factor protein RarA
31-30705..32570 [+], 1866Sodium:proton antiporter
32-32596..35247 [+], 2652Excinuclease ABC subunit A
33-35328..37166 [-], 1839Integrating conjugative element relaxaseRelaxase, MOBH Family
34-37484..38110 [+], 627hypothetical protein
35-38123..38755 [+], 633hypothetical protein
36-38840..39205 [+], 366hypothetical protein
37-39217..40737 [-], 1521TraG-like proteinTfc19, T4SS component 
38-40753..41109 [-], 357hypothetical protein
39-41106..42500 [-], 1395Integrating conjugative element proteinTfc22, T4SS component 
40-42510..43457 [-], 948TraU proteinTfc23, T4SS component 
41-43454..43900 [-], 447hypothetical proteinTfc24, T4SS component 
42-44062..44556 [-], 495DNA repair protein RadC
43-44732..45496 [-], 765Disulfide bond formation protein DsbA
44-45510..48377 [-], 2868Conjugative transfer ATPaseTfc16, T4SS component 
45-48377..48817 [-], 441Conjugal transfer proteinTfc15, T4SS component 
46-48798..50216 [-], 1419Integrating conjugative element proteinTfc14, T4SS component 
47-50206..51111 [-], 906Integrating conjugative element proteinTfc13, T4SS component 
48-51108..51797 [-], 690Integrating conjugative element proteinTfc12, T4SS component 
49-51794..52192 [-], 399Conjugative transfer region proteinTfc11, T4SS component 
50-52204..52563 [-], 360Integrating conjugative element membrane proteinTfc10, T4SS component 
51-52580..52813 [-], 234Integrating conjugative element protein
52-52810..53193 [-], 384Integrative conjugative element proteinTfc9, T4SS component 
53-53292..54041 [-], 750Integrating conjugative element membrane proteinTfc8, T4SS component 
54-54038..56101 [-], 2064Conjugative coupling factor TraD, PFGI-1 classTfc6, T4SS component 
55-56232..56771 [-], 540Integrating conjugative element proteinTfc5, T4SS component 
56-56768..57373 [-], 606Lytic transglycosylaseTfc4, T4SS component 
57-57355..58080 [-], 726Integrating conjugative element proteinTfc3, T4SS component 
58-58095..58736 [-], 642Chromosome segregation protein SMCTfc2, T4SS component 
59-58733..59332 [-], 600Integrating conjugative element protein pill, pfgi-1Tfc2, T4SS component 
60-59480..59686 [-], 207hypothetical protein
61-59802..62081 [-], 2280DEAD/DEAH box helicase
62-62217..62522 [-], 306hypothetical protein
63-62613..62933 [-], 321hypothetical protein
64-62985..64094 [-], 1110SAM-dependent methyltransferase
65-64159..64806 [-], 648hypothetical protein
66-64883..65143 [-], 261hypothetical protein
67-65160..65567 [-], 408hypothetical protein
68-65670..65993 [-], 324hypothetical protein
69-66088..66777 [-], 690hypothetical protein
70-66835..67752 [-], 918hypothetical protein
71-68121..68474 [-], 354hypothetical protein
72-68599..69411 [-], 813hypothetical protein
73-69700..69978 [-], 279hypothetical protein
74-70076..70813 [-], 738hypothetical protein
75-70894..71580 [-], 687hypothetical protein
76-71754..72146 [-], 393hypothetical protein
77-72168..72380 [-], 213hypothetical protein
78-72712..73269 [-], 558hypothetical protein
79-73512..75119 [-], 1608DNA methyltransferase
80-75639..77651 [-], 2013DNA topoisomerase III
81-77930..78370 [-], 441Single-stranded DNA-binding protein
82-78443..78970 [-], 528hypothetical protein
83-78967..79746 [-], 780Integrating conjugative element protein
84-80065..81291 [-], 1227hypothetical protein
85-81295..81855 [-], 561hypothetical protein
86-81871..83520 [-], 1650hypothetical protein
87-83513..83761 [-], 249hypothetical protein
88-83745..84620 [-], 876cobyrinic acid a,c-diamide synthase
89-84663..84875 [-], 213phage transcriptional regulator AlpA
90-84994..85746 [-], 753hypothetical protein
91-85776..85931 [+], 156hypothetical protein
 
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer
virulence  Gene may be involved in adaptative function

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins91Fasta
(1) Botelho J; Grosso F; Peixe L (2018). Unravelling the genome of a Pseudomonas aeruginosa isolate belonging to the high-risk clone ST235 reveals an integrative conjugative element housing a blaGES-6 carbapenemase. J Antimicrob Chemother. 73(1):77-83. [PudMed:29029083]